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. Author manuscript; available in PMC: 2020 May 11.
Published in final edited form as: Nat Neurosci. 2020 Feb 10;23(4):487–499. doi: 10.1038/s41593-019-0582-1

Extended Data Fig. 4 |. innate anxiety-like and locomotor behaviors are unchanged in the absence of new myelin formation.

Extended Data Fig. 4 |

Quantification of time spent in the closed arms of the elevated plus maze (EPM) (a) and the periphery of the open field test (OFT) (b); unpaired two-tailed t-test, EPM (difference: −16.38 ± 12.29, 95% CI: −42.59 to 9.818, t15 = 1.333, p = 0.2025), OFT (difference: 20.94 ± 22.43, 95% CI: −27.17 to 69.05, t15 = 0.9334, p = 0.3664). (c) Quantification of total distance traveled in the open field test; unpaired two-tailed t-test (difference: 788.3 ± 780.0, 95% CI: −884.6 to 2461, t15 = 1.011, p = 0.3293). Heatmaps representing relative frequency (red - frequent, blue - infrequent) of cre-negative and Myrf icKO animals in the elevated plus maze (d) (dashed lines demarcate the closed arms), and open field test (e). Data are presented as mean ± SEM. For a-c, n = 5 cre-negative and 11 Myrf icKO mice.