Table 5.
Clinical outcomes (HoNOS)
Implementation site | Comparator site | |||||||||
Baseline | Year 1 | Year 2 | P value | P value | Baseline | Year 1 | Year 2 | P value | P value | |
(n=52) | (n=77) | (n=53) | Y1 vs baseline | Y2 vs baseline | (n=28) | (n=16) | (n=11) | Y1 vs baseline | Y2 vs baseline | |
Change in HoNOS scores (from referral to 1 year) | ||||||||||
1. Overactive, aggressive, disruptive or agitated behaviour | −0.56 (1.73) | −0.43 (1.72) | −0.69 (1.45) | 0.59 | 0.78 | −0.43 (1.55) | −1.06 (1.65) | −0.09 (1.14) | * | * |
2. Non-accidental self injury | −0.50 (1.38) | −0.22 (1.26) | −0.22 (1.15) | 0.18 | 0.21 | −0.25 (0.84) | −0.06 (1.29) | −0.36 (1.43) | * | * |
3. Problem drinking or drug taking | −0.40 (1.48) | −0.15 (1.87) | 0.04 (1.71) | 0.30 | 0.12 | 0.14 (1.04) | −0.31 (1.20) | −0.10 (1.52) | * | * |
4. Cognitive problems | −0.27 (1.34) | −0.15 (1.32) | −0.06 (1.32) | 0.48 | 0.33 | −0.29 (1.18) | −0.38 (0.96) | −0.50 (1.51) | * | * |
5. Physical illness or disability problems | −0.23 (1.10) | 0.03 (1.35) | 0.02 (1.08) | 0.19 | 0.17 | 0.11 (0.50) | −0.38 (1.02) | 0.45 (1.44) | * | * |
6. Problems associated with hallucinations and delusions | −0.56 (1.62) | −0.71 (1.70) | −0.11 (1.51) | 0.74 | 0.14 | −0.86 (1.46) | −1.81 (1.42) | −0.91 (1.76) | * | * |
7. Problems with depressed mood | −0.50 (1.59) | −0.19 (1.49) | −0.55 (1.12) | 0.24 | 0.94 | −0.46 (1.29) | −0.88 (1.41) | −0.55 (1.21) | * | * |
8. Other mental and behavioural problems | −0.45 (1.53) | −0.73 (1.81) | −0.27 (1.49) | 0.58 | 0.68 | −0.61 (1.26) | −0.75 (1.98) | −0.36 (1.69) | * | * |
9. Problems with relationships | −0.83 (1.32) | −0.41 (1.51) | −0.20 (1.25) | 0.07 | 0.013 | −0.21 (1.26) | −1.00 (1.41) | −0.10 (0.57) | * | * |
10. Problems with activities of daily living | −0.33 (1.57) | −0.32 (1.55) | −0.46 (1.47) | 0.85 | 0.68 | −0.64 (1.16) | −1.00 (1.55) | 0.18 (0.75) | * | * |
11. Problems with living conditions | −0.20 (1.51) | −0.33 (1.44) | 0.08 (1.21) | 0.69 | 0.28 | −0.36 (1.31) | −0.69 (1.20) | 0.45 (1.13) | * | * |
12. Problems with occupation and activities | −0.33 (1.64) | −0.19 (1.47) | 0.30 (1.45) | 0.54 | 0.037 | −0.25 (1.58) | −1.06 (1.57) | −0.09 (1.45) | * | * |
Mean (SD) change in HoNOS scores from referral to 1 year at each trust for patients accepted onto EIP pathway. Excludes EIP to EIP transfers. P values from paired t-tests.
*P values not calculated due to amount of missing data.
EIP, early intervention in psychosis; HoNOS, Health of the Nation Outcome Scales.