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. 2020 Apr 29;10(4):e033711. doi: 10.1136/bmjopen-2019-033711

Table 5.

Clinical outcomes (HoNOS)

Implementation site Comparator site
Baseline Year 1 Year 2 P value P value Baseline Year 1 Year 2 P value P value
(n=52) (n=77) (n=53) Y1 vs baseline Y2 vs baseline (n=28) (n=16) (n=11) Y1 vs baseline Y2 vs baseline
Change in HoNOS scores (from referral to 1 year)
1. Overactive, aggressive, disruptive or agitated behaviour −0.56 (1.73) −0.43 (1.72) −0.69 (1.45) 0.59 0.78 −0.43 (1.55) −1.06 (1.65) −0.09 (1.14) * *
2. Non-accidental self injury −0.50 (1.38) −0.22 (1.26) −0.22 (1.15) 0.18 0.21 −0.25 (0.84) −0.06 (1.29) −0.36 (1.43) * *
3. Problem drinking or drug taking −0.40 (1.48) −0.15 (1.87) 0.04 (1.71) 0.30 0.12 0.14 (1.04) −0.31 (1.20) −0.10 (1.52) * *
4. Cognitive problems −0.27 (1.34) −0.15 (1.32) −0.06 (1.32) 0.48 0.33 −0.29 (1.18) −0.38 (0.96) −0.50 (1.51) * *
5. Physical illness or disability problems −0.23 (1.10) 0.03 (1.35) 0.02 (1.08) 0.19 0.17 0.11 (0.50) −0.38 (1.02) 0.45 (1.44) * *
6. Problems associated with hallucinations and delusions −0.56 (1.62) −0.71 (1.70) −0.11 (1.51) 0.74 0.14 −0.86 (1.46) −1.81 (1.42) −0.91 (1.76) * *
7. Problems with depressed mood −0.50 (1.59) −0.19 (1.49) −0.55 (1.12) 0.24 0.94 −0.46 (1.29) −0.88 (1.41) −0.55 (1.21) * *
8. Other mental and behavioural problems −0.45 (1.53) −0.73 (1.81) −0.27 (1.49) 0.58 0.68 −0.61 (1.26) −0.75 (1.98) −0.36 (1.69) * *
9. Problems with relationships −0.83 (1.32) −0.41 (1.51) −0.20 (1.25) 0.07 0.013 −0.21 (1.26) −1.00 (1.41) −0.10 (0.57) * *
10. Problems with activities of daily living −0.33 (1.57) −0.32 (1.55) −0.46 (1.47) 0.85 0.68 −0.64 (1.16) −1.00 (1.55) 0.18 (0.75) * *
11. Problems with living conditions −0.20 (1.51) −0.33 (1.44) 0.08 (1.21) 0.69 0.28 −0.36 (1.31) −0.69 (1.20) 0.45 (1.13) * *
12. Problems with occupation and activities −0.33 (1.64) −0.19 (1.47) 0.30 (1.45) 0.54 0.037 −0.25 (1.58) −1.06 (1.57) −0.09 (1.45) * *

Mean (SD) change in HoNOS scores from referral to 1 year at each trust for patients accepted onto EIP pathway. Excludes EIP to EIP transfers. P values from paired t-tests.

*P values not calculated due to amount of missing data.

EIP, early intervention in psychosis; HoNOS, Health of the Nation Outcome Scales.