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. 2020 Apr 29;4(1):e000630. doi: 10.1136/bmjpo-2019-000630

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Difference between rhGH treated group related to Z-stature in RCTs (RevMan 5.3). (A) Random sequence generation (selection bias). (B) Allocation concealment (selection bias). (C) Blinding of participants and personnel (performance bias). (D) Blinding of outcomes assessment (detection bias). (E) Incompleted outcome data (attrition bias), selective reporting (reporting bias). (G) Intention-to-treat. (H) Sample size determination. (I) Outcome. (J) Early interruption. (K) Prognostic characteristics. GH, growth hormone; RCTs, randomised controlled trials; rhGH, recombinant human GH.