Table 5. Univariate and Multivariate Logistic Regression Analysis to Identify Factors Contributing to Medication Adherence in Rheumatoid Arthritis Patients.

Variable	Univariate regression analysis				Multivariate logistic regression
	Odds ratio	95% CI		p value	Odds ratio	95% CI		p value
		Lower	Upper			Lower	Upper
Demographic characters
Education level	0.68	0.51	0.91	0.010*	0.72	0.49	1.06	0.092
House income	0.78	0.65	0.94	0.010*	0.93	0.73	1.18	0.537
Diabetes mellitus	2.44	1.05	5.69	0.039*	3.00	1.12	8.07	0.030*
Medication characters
Number of daily prescription drugs	1.25	1.03	1.53	0.026*	1.16	0.89	1.52	0.265
Prednisolone dose	1.16	1.02	1.31	0.025*	1.12	0.94	1.32	0.200
Frequency of DMARDs change	1.88	1.03	3.42	0.914	0.96	0.63	1.46	0.846
Clinical characters
Early rheumatoid arthritis (≤2 years)	1.29	0.65	2.56	0.454	1.07	0.91	1.26	0.428
DAS-28 (CRP)	1.07	0.84	1.36	0.594	1.02	0.99	1.05	0.220
Personality traits
High extroversion	1.08	0.55	2.13	0.817	0.88	0.39	2.00	0.763
High agreeableness	1.14	0.64	2.05	0.657	1.23	0.60	2.50	0.577
High conscientiousness	2.27	1.18	4.09	0.013*	2.11	1.01	4.38	0.046*
High neuroticism	1.00	0.41	2.47	1.000	0.71	0.24	2.08	0.532
High openness	0.96	0.48	1.93	0.906	1.10	0.48	2.53	0.821

CI, confidence interval; DMARDs, disease-modifying anti-rheumatic drugs; DAS-28, Disease Activity Score using 28 joints; CRP, C-reactive protein.

^*p<0.05.