Table 2.

Recent studies on circRNAs as diagnostic biomarkers of HCC

circBase ID (Alias)	Gene symbol	Genomic position	AUC	Sensitivity (%)	Specificity (%)	Ref.
Circ‐CDYL, plus HDGF and HIF1AN	‐	‐	0.73	75.4	66.67	9
hsa_circ_001565	B4GALT2	chr1:44446997‐44447136	‐	73.5	82.29	71
hsa_circ_000224	C17orf107	chr17:4803230‐4803902	‐	95.6	92.7	71
hsa_circ_000520	VIM	chr10:17271723‐17271867	‐	97.1	89.6	71
hsa_circ_0016788	TRIM11	chr1:228581376‐228594517	0.851	‐	‐	59
hsa_circ_0128298	SPINK1	chr5:147210311‐147211162	0.668	71.6	81.5	72
hsa_circ_0001727 (CirZKSCAN1)	ZKSCAN1	chr7:99621041‐99621930	0.834	82.2	72.4	48
hsa_circ_0000976, plus hsa_circ_0007750 and hsa_circ_0139897	HPCAL1, RABGGTA, and MTM1, respectively	chr2:10559859‐10560261, chr14:24735635‐24737825, and chrX:149761066‐149787612, respectively	0.843	87.5	81.2	73
hsa_circRNA_104075	NUP153	chr6:17669524‐17669777	0.973	96.0	98.3	39
hsa_circ_0005075	EIF4G3	chr1:21377358‐21415706	0.94	83.3	90.0	67
hsa_circ_0028502	SLC24A6	chr12:113753139‐113754806	0.675	72.1	58.0	70
hsa_circ_0076251	ZFAND3	chr6:38050167‐38084515	0.738	71.3	64.0	70
hsa_circ_0027089	PTGES3	chr12:57059987‐57064148	0.784	57.8	84.8	68
hsa_circ_0003998	ARFGEF2	chr20:47570092‐47580435	0.894	84.0	80.0	69

Abbreviations: ‐, not provided; AUC, area under the curve.