Table 2.
Baseline characteristics by frailty group
| Characteristic | Nonfrail (n = 828) | Frail (n = 790) |
|---|---|---|
| Age, n (%) | ||
| Median (range), years | 70 (40–80) | 77 (44–92) |
| <65 years | 66 (8) | 26 (3) |
| 65–75 years | 754 (91) | 299 (38) |
| 76–80 years | 74 (9) | 290 (37) |
| >80 years | 0 | 201 (25) |
| Sex, n (%) | ||
| Male | 436 (53) | 415 (53) |
| Female | 392 (47) | 375 (47) |
| ECOG performance status, n (%)a | ||
| 0 | 401 (48) | 73 (9) |
| 1 | 427 (52) | 368 (47) |
| 2 | 0 | 343 (43) |
| 3 | 0 | 6 (<1) |
| Data not available | 0 | 0 |
| International Staging System stage, n (%)b | ||
| I or II | 575 (69) | 419 (53) |
| III | 253 (31) | 371 (47) |
| Lactate dehydrogenase, n (%) | ||
| <200 U/L | 707 (85) | 612 (78) |
| ≥200 U/L | 120 (15) | 177 (22) |
| Missing data | 1 | 1 |
| Creatinine clearance, n (%) | ||
| <60 mL/min | 299 (36) | 478 (61) |
| <30 mL/min | 38 (5) | 108 (14) |
| ≥60 mL/min | 529 (64) | 312 (39) |
ECOG Eastern Cooperative Oncology Group
aECOG scores range from 0 to 5, with higher numbers indicating greater disability
bHigher stages indicate more severe disease