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. 2019 Oct 8;34(3):938–941. doi: 10.1038/s41375-019-0587-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — DNMTi treatment shows additive effect with ATRA in ADCC assays. Results from ADCC assays with azacytidine (a) and decitabine (b). Cell lysis is depicted on the y-axis with increasing concentrations of daratumumab (x-axis). The percent lysis by ADCC was calculated as outlined in the Methods section. Colors indicate the treatments, and fold change in CD38 MFI are given in brackets (red). Depicted is one representative experiment from two independent experiments. The p-values at 10 ug/ml concentration are given below in the table. Asterisk indicates a significant difference (p ≤ 0.05) and NS indicates p > 0.05 (paired student’s t-test)