Table 2.
Clinical characteristics according to endoscopic atrophy
| Characteristic | Mild atrophy (n = 49) | Severe atrophy (n = 137) | p value |
|---|---|---|---|
| Age, yr | 61.1 ± 8.4 | 64.1 ± 9.0 | 0.040 |
| Sex | 0.226 | ||
| Male | 28 (57.1) | 92 (67.1) | |
| Female | 21 (42.9) | 45 (32.6) | |
| Pathology of gastric neoplasm | 0.885 | ||
| LGD | 21 (42.9) | 61 (44.5) | |
| HGD | 11 (22.4) | 26 (19.0) | |
| EGC | 17 (34.7) | 50 (36.5) | |
| Helicobacter pylori infection status | 0.370 | ||
| Present | 18 (36.7) | 40 (29.2) | |
| Absent | 31 (63.3) | 97 (70.8) | |
| Location | 0.925 | ||
| Upper | 9 (18.4) | 26 (19.05) | |
| Lower | 40 (81.6) | 111 (81.0) | |
| Serological atrophy | 0.000 | ||
| Positive | 9 (18) | 83 (61) | |
| Negative | 40 (82) | 54 (39) | |
| Serum level, ng/mL | |||
| sPG I | 78.6 ± 52.6 | 46.7 ± 37.4 | 0.000 |
| sPG II | 21.1 ± 15.3 | 17.1 ± 11.6 | 0.058 |
| sPG I/II ratio | 4.2 ± 1.8 | 2.9 ± 1.6 | 0.000 |
| Intragastric pH | 6.1 ± 1.2 | 6.3 ± 1.2 | 0.332 |
Values are presented as mean ± SD or number (%).
LGD, low grade dysplasia; HGD, high grade dysplasia; EGC, early gastric cancer; sPG, serum pepsinogen.