Table 3.
Clinical characteristics according to Helicobacter pylori and serologic atrophy status
| Characteristic | Serologic atrophy group (n = 92) |
Serologic non-atrophy group (n = 94) |
||
|---|---|---|---|---|
| H. pylori (+) (n = 27) | H. pylori (–) (n = 65) | H. pylori (+) (n = 31) | H. pylori (–) (n = 63) | |
| Age, yr | 59.7 ± 10.0 | 65.4 ± 8.3 | 59.0 ± 8.3 | 65.0 ± 8.4 |
| Sex, male:female | 15:12 | 46:19 | 15:16 | 44:19 |
| Pathology | ||||
| LGD | 13 | 31 | 17 | 21 |
| HGD | 8 | 12 | 6 | 11 |
| EGC | 6 | 22 | 8 | 31 |
| Degree of atrophy | ||||
| Mild | 9 (9.8) | 40 (42.6) | ||
| 4 (14.8) | 5 (7.7) | 14 (45.2) | 26 (41.3) | |
| Severe | 83 (90.2) | 54 (57.4) | ||
| 23 (85.2) | 60 (92.3) | 17 (54.8) | 37 (58.7) | |
| Serum level, ng/mL | ||||
| sPG I | 38.6 ± 18.7 | 30.0 ± 18.5 | 95.3 ± 49.4 | 68.6 ± 48.3 |
| sPG II | 18.1 ± 5.8 | 14.6 ± 8.0 | 28.9 ± 16.9 | 16.5 ± 13.9 |
| sPG I/II ratio | 2.1 ± 0.6 | 2.0 ± 0.7 | 3.6 ± 1.3 | 4.8 ± 1.8 |
| Intragastric pH | 6.4 ± 0.6 | 6.5 ± 0.9 | 6.3 ± 1.4 | 5.8 ± 1.4 |
Values are presented as mean ± SD or number (%).
LGD, low grade dysplasia; HGD, high grade dysplasia; EGC, early gastric cancer; sPG, serum pepsinogen.