Figure 1.

Effect of thymic stromal lymphopoietin (TSLP) and chemoattractant receptor homologous molecule expressed on Th2 (CRTH2) antagonist on airway hyperresponsiveness (AHR) to methacholine. AHR was measured 24 hours after the final ovalbumin (OVA) challenge using a Flexivent system in which mice were exposed to increasing concentrations of methacholine (6.25 to 50 mg/mL). Values are expressed as mean ± SEM (n = 5 to 8/group). CON, control. ^a p < 0.001 compared with the CON group, ^b p < 0.001 compared with the OVA group.