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. 2020 May 11;11(5):345. doi: 10.1038/s41419-020-2501-5

Fig. 5. miR-6086 targeted OC2 and EGFL6 and suppressed their expression in ovarian cancer.

Fig. 5

a, d Schematic representation of potential binding sites of miR-6086 on 3′UTRs of OC2 (a) and EGFL6 (d) and the mutant sites. b, e Protein expression of OC2 (b) and EGFL6 (e) after treated with miR-6086 in Caov3 and Skov3, followed by Western blotting assay. c, f The effects of miR-6086 overexpression on the relative luciferase activity of plasmids containing WT or Mut 3′UTRs of OC2 (c) and EGFL6 (f) mRNAs. Data are shown as mean ± SD of three independent experiments. *P < 0.05; **P < 0.01. (i) Caov3, (ii) Skov3.