Figure 2.

Distribution of homologs within clusters for TMHMM dataset. Proteins with membrane helix outside the signal peptide were clustered, and cluster composition was quantified. Majority of the clusters had, as expected, at least seven proteins, one from each of the analyzed strains, defining the core group. Clusters with six or less components are in principle defined as accessory proteins from the pangenome. Only core proteins were considered for immunogenic analysis.