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. 2020 Feb 12;13(3):618–627. doi: 10.1111/cts.12748

Table 3.

Prevalence of actionability using CPIC guidelines and FDA labeling

Medication data available (N = 600) CPIC FDA
Genetic resultsa
Actionable result (i.e., may be actionable now or in the future) 595 523
No actionable result 5 77
Current prescriptions affected by PGx results
Current prescription for an affected drugb 277 168
Recommendation: modify usec 97 27
Recommendation: regular use 180 141
No current prescription for an affected drug 323 432

CPIC, Clinical Pharmacogenetics Implementation Consortium; FDA, US Food and Drug Administration; PGx, pharmacogenomics.

a

More patients possessed an actionable results per CPIC than the FDA (P < 0.0001).

b

More patients possessed a prescription for drug affected by PGx results per CPIC than the FDA (P < 0.0001).

c

More patients possessed an actionable result for a medication they were currently prescribed per CPIC than the FDA (P < 0.0001).