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. 2020 May 5;8:296. doi: 10.3389/fcell.2020.00296

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Copyright © 2020 Ramírez-Bajo, Martín-Ramírez, Bruno, Pasquino, Banon-Maneus, Rovira, Moya-Rull, Lazo-Rodriguez, Campistol, Camussi and Diekmann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of CsA-induced nephrotoxicity on mice body weight recorded weekly during the model. (A) Preventive treatment. (B) Curative treatment. (CsA, n = 70), (BM-MSCs, n = 35), (EVs, n = 34), and (dCM, n = 16) *Significantly different when compared CsA versus control group (^∗∗∗P < 0.001). #Significantly different when compared CsA versus treatment groups (^#P < 0.05). Data are expressed as mean ± SEM. One-way analysis of variance (ANOVA) followed by Dunnett’s multiple comparisons test was used to compare group’s means.