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Summary of effects of BM-MSCs, EVs and dCM therapies in a murine model of CsA nephrotoxicity at the end of the study.
| Treatment | Cell therapy | Survival | Body weight | BUN levels | Histology | ||
| Vacuolization | Cast | Cyst | |||||
| Preventive | BM-MSCs | = | = | = | = | = | ↓ |
| EVs | = | = | = | = | = | = | |
| dCM | = | = | = | = | = | ↓ | |
| Curative | BM-MSCs | = | ↑ | ↓ | ↓ | ↓ | ↓ |
| EVs | = | ↑ | = | = | = | ↓ | |
| dCM | = | ↑ | = | = | = | = | |
=, no change; ↑, increase; and ↓, decrease.
