Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
SP1/AKT/FOXO3 signaling pathway mediates the effect of miR-362-3p in RCC cells. (A,B) Western blotting analysis demonstrating the effect of miR-362-3p or siSP1 on the protein level of p-AKT, p-FOXO3, p-RB, CCND1 and Snail in RCC cells. (C,D) FOXO3 activity was strongly activated by upregulation of miR-362-3p or by knockdown of SP1 expression in RCC cells, *P < 0.05.
