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. 2020 May 5;12:113. doi: 10.3389/fnagi.2020.00113

FIGURE 6.

FIGURE 6

Microglial density and activation in the hippocampus of female 3xTg-AD mice. Microglia in the hippocampus were immunostained with Iba-1 antibody, counted, and morphologically characterized as either activated or resting. Microglia cell density was measured in (A) early-MA and (C) late-MA mice. The percent of microglia exhibiting activated morphology was determined in (B) early-MA and (D) late-MA mice. Significance is p < 0.05. D = significant main effect of diet; H = significant main effect of hormone treatment.