Table 5.

Pharmacokinetic parameters of groups with various renal function status estimated with Bayesian method (n = 136, mean ± SD).

Group	N	V1 (L/kg)		V2 (L/kg)		CL (L/h/kg)		Q (L/h/kg)
		Estimate	95%CI	Estimate	95%CI	Estimate	95%CI	Estimate	95%CI
eGFR ≥ 130	43	0.29 ± 0.51	0.13–0.45	1.36 ± 0.41	1.24−1.49	0.015 ± 0.002	0.014–0.015	0.016 ± 0.008	0.014−0.019
90 ≤ eGFR < 130	62	0.27 ± 0.24	0.21−0.33	1.79 ± 0.75	1.60−1.98	0.013 ± 0.002	0.013−0.014	0.023 ± 0.014	0.019−0.026
60 ≤ eGFR < 90	23	0.26 ± 0.16	0.19−0.33	1.71 ± 0.63	1.44−1.99	0.010 ± 0.001	0.010−0.011	0.022 ± 0.010	0.018−0.027
30 ≤ eGFR < 60	8	0.33 ± 0.32	0.06−0.60	2.28 ± 1.47	1.05−3.52	0.008 ± ± 0.003	0.006−0.010	0.027 ± 0.017	0.013−0.041
Total	136	0.28 ± 0.34	0.22−0.33	1.67 ± 0.74	1.55−1.80	0.013 ± 0.003	0.012−0.013	0.021 ± 0.012	0.019−0.023
P value		0.954		0.002		0.001		0.017

eGFR is given in ml/min·1.73m².