Table 1.

Numbers of worms recovered and percent efficacy for each treatment group. All dogs were infected with 300 A. caninum L3 on day 0, were treated on day 24, and were euthanized and worms recovered on day 34. Statistical comparisons were performed using the Wilcoxon's Rank Sum test.

Treatment Groupa	No. ofdogs	Numbers of worms per dog (range)	Geometric mean b number of worms per dog	% Efficacy c
Pyrantel pamoate	8	63–105	74.8a	23.2
Fenbendazole	8	57–94	72.0a	26.1
Milbemycin oxime	8	55–115	88.9	8.8
Emodepside + praziquantel	8	0–1	0.4a	99.6
Non-treated control	8	71–132	97.4	NA

NA: Not applicable.

Statistically significant compared to the non-treated control group (p < 0.05).

^aNemex®-2 (pyrantel pamoate), Panacur® C (fenbendazole), Interceptor® (milbemycin oxime).

^bWorm counts were logarithmically transformed (ln [count + 1]), averaged and then back-transformed to approximate the geometric means.

^cEfficacy was calculated using the formula: [(geometric mean worm count control group – geometric mean worm count treated group)/(geometric mean worm count control group)] x 100.