Table S1. Phosphorus, FGF23, and Klotho level of the patients that completed the 52-week follow-up.

Variable	Placebo (n=37)				NAM (n=35)			P‡
	Baseline	52nd week	P*		Baseline	52nd week	P†
Phosphorus (mmol/L)	2.48±0.53	2.29±0.70	0.180		2.47±0.55	2.19±0.56	0.039	0.51
FGF23 (ng/L)	87.21±32.32	81.33±19.99			86.07±25.42	77.05±18.41
KLOTHO (ng/L)	1,043.49±487.02	912.73±506.64			1,068.06±469.17	1,053.85±341.66

Data are reported as the mean ± SD or (for variables with a non-Gaussian distribution) the median (interquartile range). *, the 52^nd week versus the baseline in the placebo group; ^†, the 52^nd week versus the baseline in the NAM group; ^‡, the placebo group versus the NAM group on the 52^nd week. NAM, nicotinamide.