Table 3. Relationship between MTL and SBP, DBP, hypertension in different models.
| Exposure variables | Model I | Model II | Model IIIabc |
|---|---|---|---|
| SBP (mmHg)* | |||
| MTL (per 1T/S increment) | –8.11 (–9.58, –6.64), <0.01 | 1.74 (0.28, 3.20), 0.02 | 0.25 (–1.59, 2.10), 0.79 |
| MTL (quartiles) | |||
| Q1 | Ref | Ref | Ref |
| Q2 | –3.09 (–4.18, –2.00), <0.01 | 0.06 (–0.95, 1.07), 0.91 | –1.29 (–2.54, –0.04), 0.04 |
| Q3 | –4.67 (–5.76, –3.58), <0.01 | 0.68 (–0.37, 1.72), 0.20 | –0.80 (–2.08, 0.48), 0.22 |
| Q4 | –5.75 (–6.84, –4.66), <0.01 | 1.16 (0.08, 2.23), 0.04 | 0.22 (–1.12, 1.57), 0.74 |
| P for trend | <0.01 | 0.02 | 0.66 |
| DBP (mmHg)* | |||
| MTL (per 1T/S increment) | –1.14 (–2.32, 0.05), 0.06 | 1.15 (–0.12, 2.41), 0.08 | –0.58 (–2.11, 0.95), 0.45 |
| MTL (quartiles) | |||
| Q1 | Ref | Ref | Ref |
| Q2 | 0.15 (–0.73, 1.03), 0.73 | 0.99 (0.11, 1.86), 0.03 | 0.92 (–0.12, 1.96), 0.08 |
| Q3 | 0.22 (–0.66, 1.10), 0.62 | 1.58 (0.67, 2.48), <0.01 | 1.26 (0.19, 2.32), 0.02 |
| Q4 | –0.74 (–1.62, 0.13), 0.09 | 0.96 (0.03, 1.89), 0.04 | –0.36 (–1.47, 0.76), 0.53 |
| P for trend | 0.13 | 0.03 | 0.75 |
| Hypertension# | |||
| MTL (per 1T/S increment) | 0.16 (0.12, 0.21), <0.01 | 1.41 (1.01, 1.98), 0.05 | 0.12 (0.02, 0.94), 0.04 |
| MTL (quartiles) | |||
| Q1 | Ref | Ref | Ref |
| Q2 | 0.59 (0.50, 0.70), <0.01 | 0.99 (0.81, 1.21), 0.92 | 0.52 (0.15, 1.85), 0.31 |
| Q3 | 0.43 (0.36, 0.52), <0.01 | 1.18 (0.95, 1.47), 0.14 | 0.44 (0.11, 1.76), 0.25 |
| Q4 | 0.32 (0.26, 0.38), <0.01 | 1.16 (0.91, 1.48), 0.23 | 0.31 (0.07, 1.31), 0.11 |
| P for trend | <0.01 | 0.11 | <0.01 |
*, Data are expressed as β (95% CI), P value; #, data are expressed as OR (95% CI), P value. Model I adjust for: None; Model II adjust for: age, gender and BMI; Model III adjust for: a, (SBP) age, gender, BMI, FBG, DBP, TC, HDL-C, TG, LDL-C, CRP, eGFR, alcohol consumption, smoking and antihypertensive drugs; b, (DBP) age, gender, BMI, FBG, SBP, TC, HDL-C, TG, LDL-C, CRP, eGFR, alcohol consumption smoking and antihypertensive drugs; c, (hypertension) age, gender, BMI, FBG, SBP, TC, TG, HDL-C, CRP, eGFR, alcohol consumption, smoking and antihypertensive drugs. MTL, mean telomere length; SBP, systolic blood pressure; DBP, diastolic blood pressure; Q, quartiles; CI, confidence interval; OR, odds ratio; BMI, body mass index; FBG, fasting blood glucose; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate.