| Age |
|
|
|
|
|
|
|
|
| 18–29 |
1,312 |
0.58 |
|
675 |
0.59 |
|
637 |
0.56 |
| 30–39 |
10,532 |
4.62 |
|
5,198 |
4.56 |
|
5,334 |
4.68 |
| 40–49 |
39,364 |
17.27 |
|
19,706 |
17.29 |
|
19,658 |
17.24 |
| 50–59 |
58,777 |
25.78 |
|
29,349 |
25.75 |
|
29,428 |
25.82 |
| 60–69 |
64,635 |
28.35 |
|
32,351 |
28.38 |
|
32,284 |
28.32 |
| 70–79 |
39,275 |
17.23 |
|
19,683 |
17.27 |
|
19,592 |
17.19 |
| ≥80 |
14,094 |
6.18 |
|
7,034 |
6.17 |
|
7,060 |
6.19 |
| Race |
|
|
|
|
|
|
|
|
| White |
181,350 |
79.54 |
|
90,727 |
79.59 |
|
90,623 |
79.50 |
| Black |
24,372 |
10.69 |
|
12,116 |
10.63 |
|
12,256 |
10.75 |
| American Indian/Alaska Native |
1,349 |
0.59 |
|
658 |
0.58 |
|
691 |
0.61 |
| Asian or Pacific Islander |
20,918 |
9.18 |
|
10,495 |
9.21 |
|
10,423 |
9.14 |
| Marital status |
|
|
|
|
|
|
|
|
| Married |
137,213 |
60.18 |
|
68,725 |
60.29 |
|
68,488 |
60.08 |
| Unmarried |
90,776 |
39.82 |
|
45,271 |
39.71 |
|
45,505 |
39.92 |
| Subtypes |
|
|
|
|
|
|
|
|
| HR+/HER2− |
170,135 |
74.62 |
|
85,005 |
74.57 |
|
85,130 |
74.68 |
| HR+/HER2+ |
23,377 |
10.25 |
|
11,684 |
10.25 |
|
11,693 |
10.26 |
| HR−/HER2+ |
9,083 |
3.98 |
|
4,545 |
3.99 |
|
4,538 |
3.98 |
| Triple negative |
25,394 |
11.14 |
|
12,762 |
11.20 |
|
12,632 |
11.08 |
| Histology |
|
|
|
|
|
|
|
|
| Infiltrating duct carcinoma |
174,174 |
76.40 |
|
87,054 |
76.37 |
|
87,120 |
76.43 |
| Lobular carcinoma |
20,107 |
8.82 |
|
9,995 |
8.77 |
|
10,112 |
8.87 |
| Other |
33,708 |
14.78 |
|
16,947 |
14.87 |
|
16,761 |
14.70 |
| Location |
|
|
|
|
|
|
|
|
| Nipple |
752 |
0.33 |
|
364 |
0.32 |
|
388 |
0.34 |
| Central portion of breast |
11,433 |
5.01 |
|
5,682 |
4.98 |
|
5,751 |
5.05 |
| Upper-inner quadrant of breast |
32,717 |
14.35 |
|
16,389 |
14.38 |
|
16,328 |
14.32 |
| Lower-inner quadrant of breast |
14,266 |
6.26 |
|
7,082 |
6.21 |
|
7,184 |
6.30 |
| Upper-outer quadrant of breast |
89,370 |
39.20 |
|
44,831 |
39.33 |
|
44,539 |
39.07 |
| Lower-outer quadrant of breast |
19,702 |
8.64 |
|
9,862 |
8.65 |
|
9,840 |
8.63 |
| Axillary tail of breast |
1,131 |
0.50 |
|
566 |
0.50 |
|
565 |
0.50 |
| Overlapping lesion of breast |
58,618 |
25.71 |
|
29,220 |
25.63 |
|
29,398 |
25.79 |
| Laterality |
|
|
|
|
|
|
|
|
| Right: origin of primary |
112,772 |
49.46 |
|
56,601 |
49.65 |
|
56,171 |
49.28 |
| Left: origin of primary |
115,217 |
50.54 |
|
57,395 |
50.35 |
|
57,822 |
50.72 |
| Grade |
|
|
|
|
|
|
|
|
| Well differentiated; Grade I |
54,613 |
23.95 |
|
27,335 |
23.98 |
|
27,278 |
23.93 |
| Moderately differentiated; Grade II |
100,854 |
44.24 |
|
50,321 |
44.14 |
|
50,533 |
44.33 |
| Poorly differentiated; Grade III |
72,025 |
31.59 |
|
36,097 |
31.67 |
|
35,928 |
31.52 |
| Undifferentiated; anaplastic; Grade IV |
497 |
0.22 |
|
243 |
0.21 |
|
254 |
0.22 |
| Tumor size, cm |
|
|
|
|
|
|
|
|
| ≤1 |
58,349 |
25.59 |
|
29,078 |
25.51 |
|
29,271 |
25.68 |
| ≤2 |
83,314 |
36.54 |
|
41,809 |
36.68 |
|
41,505 |
36.41 |
| ≤3 |
45,279 |
19.86 |
|
22,700 |
19.91 |
|
22,579 |
19.81 |
| ≤4 |
18,282 |
8.02 |
|
9,111 |
7.99 |
|
9,171 |
8.05 |
| ≤5 |
8,750 |
3.84 |
|
4,359 |
3.82 |
|
4,391 |
3.85 |
| >5 |
14,015 |
6.15 |
|
6,939 |
6.09 |
|
7,076 |
6.21 |
| Positive regional nodes number |
|
|
|
|
|
|
|
|
| 0 |
162,133 |
71.11 |
|
81,105 |
71.15 |
|
81,028 |
71.08 |
| 1–3 |
48,687 |
21.35 |
|
24,354 |
21.36 |
|
24,333 |
21.35 |
| 4–9 |
11,831 |
5.19 |
|
5,831 |
5.12 |
|
6,000 |
5.26 |
| ≥10 |
5,338 |
2.34 |
|
2,706 |
2.37 |
|
2,632 |
2.31 |
| Bone metastasis |
|
|
|
|
|
|
|
|
| No |
226,355 |
99.28 |
|
113,193 |
99.30 |
|
113,162 |
99.27 |
| Yes |
1,634 |
0.72 |
|
803 |
0.70 |
|
831 |
0.73 |
| Brain metastasis |
|
|
|
|
|
|
|
|
| No |
227,892 |
99.96 |
|
113,946 |
99.96 |
|
113,946 |
99.96 |
| Yes |
97 |
0.04 |
|
50 |
0.04 |
|
47 |
0.04 |
| Liver metastasis |
|
|
|
|
|
|
|
|
| No |
227,393 |
99.74 |
|
113,689 |
99.73 |
|
11,3704 |
99.75 |
| Yes |
596 |
0.26 |
|
307 |
0.27 |
|
289 |
0.25 |
| Lung metastasis |
|
|
|
|
|
|
|
|
| No |
227,342 |
99.72 |
|
113,662 |
99.71 |
|
113,680 |
99.73 |
| Yes |
647 |
0.28 |
|
334 |
0.29 |
|
313 |
0.27 |
