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. 2020 May 5;7:193. doi: 10.3389/fvets.2020.00193

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Copyright © 2020 Turchetto, Obber, Rossi, D'Amelio, Cavallero, Poli, Parisi, Lanfranchi, Ferrari, Dellamaria and Citterio.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemical staining of skin in northern chamois (Rupicapra r. rupicapra) affected by sarcoptic mange. The following pictures are further evidenced by black arrows: (A) Diffuse macrophages infiltration in the superficial dermis in grade 2 sarcoptic mange (IHC, anti CD68 antibody, DAB chromogen, and hematoxylin counterstain, bar = 300 μm). (B) Numerous T lymphocytes in the superficial dermis of a chamois with grade 2 sarcoptic mange (IHC, anti CD3 antibody, DAB chromogen, and hematoxylin counterstain, bar = 300 μm). (C) Increased B lymphocytes infiltration in the superficial dermis in a grade 3 sarcoptic mange (IHC, anti CD79a antibody, DAB chromogen, and hematoxylin counterstain, bar = 300 μm). (D) Scattered T lymphocytes among B cells in a grade 3 lesion (IHC, anti CD3 antibody, DAB chromogen, and hematoxylin counterstain, bar = 300 μm). Further details available in Salvadori et al. (40).