Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 5;11:785. doi: 10.3389/fimmu.2020.00785

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Wang, Yin, Yuan, Liu, Hu, Zou and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

cSPH11 and cSPH50 are cofactors in PPO activation. (A) PO activity was increased significantly in the presence of procSPH11 and procSPH50. The experimental groups were the same with Figure 3B, instead of factor Xa mutants, wild type procSPHs were used to measure PO activity (upper panel), which was represented as mean ± SD of three independent experiments. ***p < 0.001. (B) Proteolytic activation of procSPH11 and proSPH50 by cSP6_Xa. Factor Xa activated cSP6_Xa (50 ng) was incubated with 100 ng procSPH11 (left panel) or procSPH50 (right panel) for 1 h. The mixtures were analyzed by immunoblotting using anti-cSPH11 or anti-cSPH50 antibody.