TABLE 1.
Relative abundance ratio of bacteria after 20 weeks of ESM supplementation
| Roles | Species | 20 Weeks | |||
|---|---|---|---|---|---|
| HFD versus CON | HESM versus HFD | ||||
| Ratio | p‐value | Ratio | p‐value | ||
| Obesity‐related bacteria | Blautia coccoides | 2.7027 | .0003 | 0.7150 | .0840 |
| Lactobacillus reuteri | 1.6430 | .5999 | 3.4053 | .0827 | |
| Parabacteroides goldsteinii | 1.6424 | .1111 | 0.5288 | .0608 | |
| Akkermansia muciniphila | 1.8095 | .3165 | 0.0274 | .0382 | |
| Inflammation‐related bacteria | Roseburia faecis | 5.7825 | .0143 | 0.0405 | .0075 |
| Ruminococcus callidus | 1.9611 | .0011 | 0.5014 | .0135 | |
| Helcococcus ovis | 0.5961 | .1609 | 2.9279 | .0557 | |
| Aerococcus christensenii | 1.0406 | .9403 | 3.2613 | .0854 | |
| Bifidobacterium scardovii | 0.0359 | .0612 | 0.0000 | .0789 | |
| Capnocytophaga cynodegmi | 4.7996 | .0972 | 0.0000 | .0375 | |
| Desulfovibrio fairfieldensis | 0.0000 | .1407 | 0.0228/0.0000 | .0745 | |
| Blautia hydrogenotrophica | 2.8189 | .0032 | 0.5484 | .0187 | |
| Diabetes‐related bacteria | Slackia heliotrinireducens | 0.6799 | .5259 | 8.5204 | .0320 |
| Oxidative stress‐related bacteria | Bifidobacterium thermophilum | 0.1047 | .1076 | 0.0000 | .0961 |
Firmicutes: Blautia coccoides, Lactobacillus reuteri, Roseburia faecis, Ruminococcus callidus, Helcococcus ovis, Aerococcus christensenii, Blautia hydrogenotrophica; Actinobacteria: Bifidobacterium thermophilum, Slackia heliotrinireducens, Bifidobacterium scardovii; Bacteroidetes: Parabacteroides goldsteinii, Capnocytophaga cynodegmi; Verrucomicrobia: Akkermansia muciniphila; Proteobacteria: Desulfovibrio fairfieldensis.
Abbreviations: CON, control mice; HESM, high‐fat diet mice + 8% eggshell membrane powder; HFD, high‐fat diet mice.