Table 3.
Variation in male/female ratio (95% CI) for alternative AHI definitions, adjusted for age, BMI, waist circumference, and smoking status
AHI definitions: varying both apnea and hypopnea definitions, or position | M/F log AHI ratio; 95% CI |
---|---|
AHI4P | 1.92 (1.75, 2.10) |
AHI4P-non-supine | 1.67 (1.51, 1.85) |
AHI4P-supine | 1.99 (1.81, 2.19) |
AHI4P-NREM | 2.49 (2.25, 2.76) |
AHI4P-REM | 1.14 (1.04, 1.24) |
AHI4PA | 1.81 (1.70, 1.93) |
AHI3P | 1.82 (1.69, 1.96) |
AHI3PA | 1.72 (1.62, 1.82) |
See online Data Supplement for full definitions of each AHI.
AHI4P = AHI that includes apneas and hypopneas associated with at least 4% oxygen desaturation.
AHI4P-non-supine; AHI4P-supine; AHI4P-NREM; AHI4P-REM = AHI that includes apneas and hypopneas associated with at least 4% oxygen desaturation during non-supine, supine, NREM, and REM sleep respectively.
AHI4PA = AHI that includes apneas and hypopneas associated with at least 4% oxygen desaturation or with an arousal.
AHI3P = AHI that includes apneas and hypopneas associated with at least 3% oxygen desaturation.
AHI3PA = AHI that includes apneas and hypopneas associated with at least 3% oxygen desaturation or with an arousal. Statistical assessments of change in the M/F ratios comparing different definitions were based on bootstrap analyses of the change in effect estimates of each M/F ratio: AHI3PA/AHI4P: 0.90 (95% CI: 0.85, 0.95); AHI3P/AHI3PA: 0.95 (0.91, 0.99); AHI3P/AHI4P: 0.95 (0.91, 0.99); AHI4P/AHI4PA: 1.06 (1.00, 1.12); AHI4P Supine/AHI4P non-supine: 1.19 (1.06, 1.32).