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. 2019 Nov 18;43(5):zsz280. doi: 10.1093/sleep/zsz280

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© Sleep Research Society 2019. Published by Oxford University Press [on behalf of the Sleep Research Society].

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Relationships between age and hippocampal volume in Lifebrain. Left panel: GAMM was used to obtain the age-curve for hippocampal volume, using both cross-sectional and longitudinal information, covarying for sex, ICV, and study (random effect). Dotted lines represent 95% CI. Right panel: Spaghetti plot of hippocampal volume and volume change for all participants, color-coded by sample. x-Axis denotes age in years, y-axis hippocampal volume in mm³.