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. 2019 Nov 30;43(5):zsz289. doi: 10.1093/sleep/zsz289

Figure 2.

Figure 2.

Sleep architecture changes across the estrous cycle. (A) Male and female (B) bouts per hour of waking, NREM sleep, and REM sleep across 4 days of recording and the complete estrous cycle. (C) Comparison of bouts per hour of waking, NREM sleep (D), and REM sleep (E). Females were analyzed across phases of the estrous cycle using repeated measures two-way ANOVA: waking F(3, 24) = 3.37, NREM F(3, 24) = 4.91, REM F(3, 24) = 6.98. Tukey post hoc. Females were compared with males using two-way ANOVA: waking F(4, 152) =5.39, NREM F(4, 152) = 4.05, REM F(4, 152) = 8.69. Dunnett post hoc. Male (F) and female (G) average bout length for waking, NREM sleep, and REM sleep across 4 days or the estrous cycle. (H) Comparison of bout length of waking, NREM sleep (I), and REM sleep (J). For both bouts per hour and bout length, females were analyzed across phases of the estrous cycle using repeated measures two-way ANOVA: waking F(3, 24) = 3.304, NREM F(3, 24) = 23.12, REM F(3, 24) = 35.1. Tukey post hoc. *p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.0005. Females were compared with males using two-way ANOVA: waking F(4, 152) = 3.39, NREM F(4, 152) = 21.74, REM F(4, 152) = 16.95. Dunnett post hoc. #p < 0.05. Data displayed as mean ± SEM. Males n = 7, females n = 9.