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. 2020 Apr 16;21(8):2774. doi: 10.3390/ijms21082774

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Metabolic pathways including glycolysis, pentose phosphate pathway, tricarboxylic acid cycle, and lipid synthesis with target non-coding RNAs. →, promotion; ┤, inhibition; ⟳, metabolic reactions of the tricarboxylic acid cycle. Abbreviations: 3-Phosphoglyceric acid (3PG), AKT serine/threonine kinase (AKT), ATP citrate lyase (ACLY), aconitase (ACO), ⍺-Ketoglutarate dehydrogenase (⍺-KGDH), citrate synthase (CS), fructose 6-phosphate (F6P), fructose bisphosphatase (FBP), fumarase (FH), glucose 6-phosphate (G6P), glucose-6-phosphate dehydrogenase (G6PD), histone deacetylase 4 (HDAC4), glucose transporter 1 (GLUT1), hexokinase 2 (HK2), isocitrate dehydrogenase (IDH), lactate dehydrogenase A (LDHA), malate dehydrogenase (MDH), nuclear factor erythroid-2-related factor 2 (NRF2), phosphoenolpyruvate (PEP), phosphofructokinase-1 (PFK), phosphogluconate dehydrogenase (PGD), pyruvate kinase M1/2 (PKM2), pentose phosphate pathway (PPP), succinyl-CoA synthetase (SCS), succinate dehydrogenase (SDH), transketolase (TKT), wingless-type (WNT).