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. 2020 Apr 15;21(8):2741. doi: 10.3390/ijms21082741

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Extracellular vesicle (EV)-specific markers in the surface and total proteomes of human brain microvascular endothelial cells (HBMEC)-derived EVs. Venn diagram showing the overlap between the HBMEC-EV surface proteome (283 proteins) (A) or the HBMEC-EV total proteome (501 proteins) (B) and the top 100 EV marker proteins from ExoCarta. Cellular component enrichment of the identified surface (C) and total (D) EV proteomes. The identified EV proteins were enriched for cellular component using the Scaffold software.

Extracellular vesicle (EV)-specific markers in the surface and total proteomes of human brain microvascular endothelial cells (HBMEC)-derived EVs. Venn diagram showing the overlap between the HBMEC-EV surface proteome (283 proteins) (A) or the HBMEC-EV total proteome (501 proteins) (B) and the top 100 EV marker proteins from ExoCarta. Cellular component enrichment of the identified surface (C) and total (D) EV proteomes. The identified EV proteins were enriched for cellular component using the Scaffold software.