Table 5.
Biological processes and PMIDs for the EV surface unique proteins in the HIV group for the HIV vs. HIV+Aβ comparison.
| Gene Ontology (GO) Terms for Biological Processes | |||||
| Term Description | Obs | Bgr | FDR | Matching Proteins in the Network | |
| Cytoskeleton organization | 5 | 953 | 8.35 × 10−5 | ARPC4,CAP1,DNAH8,NIN,TTN | |
| Supramolecular fiber organization | 4 | 383 | 0.00011 | ARPC4,CAP1,NIN,TTN | |
| Actin filament organization | 3 | 200 | 0.0011 | ARPC4,CAP1,TTN | |
| Cellular protein-containing complex assembly | 4 | 832 | 0.0012 | ARPC4,DNAH8,NIN,TTN | |
| Actin polymerization or depolymerization | 2 | 43 | 0.0031 | ARPC4,CAP1 | |
| Protein polymerization | 2 | 83 | 0.0058 | ARPC4,NIN | |
| Localization | 5 | 5233 | 0.0296 | ARPC4,CAP1,DNAH8,NIN,TTN | |
| PMID Publications | |||||
| Term ID | Term Description | Obs | Bgr | FDR | Matching Proteins in the Network |
| PMID:21050039 | (2010) Titin A-band-specific monoclonal antibody Tit1 5H1.1. Cellular Titin as a centriolar protein in non-muscle cells. | 2 | 2 | 0.0016 | NIN,TTN |
| PMID:22985877 | (2012) Epitope of titin A-band-specific monoclonal antibody Tit1 5 H1.1 is highly conserved in several Fn3 domains of the titin molecule. Centriole staining in human, mouse and zebrafish cells. | 2 | 6 | 0.0037 | NIN,TTN |
| PMID:26655833 | (2016) The centrosome is an actin-organizing centre. | 2 | 12 | 0.0081 | ARPC4,NIN |
| PMID:27094867 | (2016) Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function. | 2 | 27 | 0.027 | NIN,TTN |
| PMID:29255378 | (2017) The human, F-actin-based cytoskeleton as a mutagen sensor. | 2 | 35 | 0.0353 | DNAH8,TTN |