Table 9.

Biological processes and PMIDs for the EV total unique proteins in the HIV group for the HIV vs. HIV+Aβ comparison.

Gene ontology (GO) Terms for Biological Processes
Term Description		Obs	Bgr	FDR	Matching Proteins in the Network
Cell envelope organization		2	3	0.0017	TGM1,TGM3
10 Most Significant PMID Publications per FDR
Term ID	Term Description	Obs	Bgr	FDR	Matching Proteins in the Network
PMID:22329734	(2012) Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair.	3	14	0.0016	KLK7,TGM1,TGM3
PMID:11093806	(2000) Transglutaminase-3, an esophageal cancer-related gene.	2	2	0.0136	TGM1,TGM3
PMID:11562168	(2001) Crystallization and preliminary X-ray analysis of human transglutaminase 3 from zymogen to active form.	2	2	0.0136	TGM1,TGM3
PMID:11980702	(2002) Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation.	2	2	0.0136	TGM1,TGM3
PMID:12850301	(2003) Analysis of epidermal-type transglutaminase (transglutaminase 3) in human stratified epithelia and cultured keratinocytes using monoclonal antibodies.	2	3	0.0136	TGM1,TGM3
PMID:14508061	(2003) A model for the reaction mechanism of the transglutaminase 3 enzyme.	2	2	0.0136	TGM1,TGM3
PMID:14645372	(2004) Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calciummagnesium.	2	2	0.0136	TGM1,TGM3
PMID:14987256	(2004) Identification of calcium-inducible genes in primary keratinocytes using suppression-subtractive hybridization.	2	8	0.0136	KLK7,TGM1
PMID:15084592	(2004) Crystal structure of transglutaminase 3 in complex with GMP: structural basis for nucleotide specificity.	2	2	0.0136	TGM1,TGM3
PMID:15172109	(2004) Transglutaminase activity and transglutaminase mRNA transcripts in gerbil brain ischemia.	2	3	0.0136	TGM1,TGM3