Table 2.

Summary of the main recent findings of epigenomic studies focused on DNAm in childhood asthma.

CpG	Chromosome:Position a	Gene/Nearest Gene	β	p-Value	Reference
ICS response
cg00066816	5:158758353	IL12B	−3.101	0.002	[38]
cg00557354	13:111767899	ARHGEF7	−3.490	0.001
cg04256470	1:10510465	CORT, CENPS	3.620	<0.001
cg09495977	4:8271507	HTRA3	−2.420	0.017
cg12333095	12:110437035	ANKRD13A	−3.485	0.001
cg13818573	17:43045372	C1QL1	−3.596	<0.001
cg21589280	1:85930152	DDAH1	−3.063	0.003
cg03080985	6:80340683	SH3BGRL2	−3.077	0.003
cg04330449	5:134871166	NEUROG1	−2.646	0.009
cg05307923	10:1779667	ADARB2	−2.577	0.011
cg08724517	4:156298205	MAP9	2.951	0.004
cg11665562	14:90723462	PSMC1	−3.250	0.001
cg14269514	1:151736130	OAZ3, MRPL9	−3.112	0.002
cg24322623	11:17740431	MYOD1	−2.964	0.004
cg27254601	16:29817104	MAZ, BOLA2	3.598	0.0005	[39]
cg15607672	14:57277228	OTX2	2.123	0.0363

^a Position based on GRCh37/hg19 build. DNAm: DNA methylation; ICS: inhaled corticosteroid.