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. 2020 Apr 20;21(8):2876. doi: 10.3390/ijms21082876

Scheme 2.

Scheme 2

Synthesis of compounds 7ac from 3. Reagents and conditions: (a) 1,2-ethylenediamine, 1,3-propanediamine and 1,4-butanediamine (0.5 eq), HOBt, DCC, CH2Cl2, rt, 12 h.