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The in vitro static clot lysis with or without magnetic guidance in vertical position was carried out as illustrated in (a). The solution appearance after blood clot lysis (b) and the solution absorbance measured at 415 nm (OD415) (c) after incubating the blood clot with PBS, PMNP, rtPA or PMNP-rtPA solution (25 μU rtPA). * p < 0.05 compared with pPMNP-rtPA without magnet.
