Figure 2.

Effect of the LCL-PLP + LCL-DOX combined therapy on the B16.F10 melanoma growth in vivo. (A,C,E): for each experimental group, tumor volumes at day 15 after tumor cell inoculation were compared with the tumor volumes from control group measured at the same time point: (B,D,F): areas under the tumor growth curves (AUTC) until day 15. The results were expressed as mean ± SD of tumor volumes of five mice. ns—not significant (p > 0.05); * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.