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. 2020 Apr 16;21(8):2767. doi: 10.3390/ijms21082767
AMPK AMP-activated protein kinase
Apaf apoptotic peptidase-activating factor
ARE antioxidant response element
ASK1 apoptosis signal-regulating kinase
ATF activating transcription factor
ATM ataxia telangiectasia mutated kinase
Bad Bcl-2 associated agonist of cell death
Bak Bcl-2 homologous antagonist/killer
Bax Bcl-2-associated X
Bcl B-cell lymphoma protein
BH Bcl-2 homology domain
Bid BH3 interacting-domain death agonist
Bim Bcl-2-like protein 11
BRCA breast cancer gene
CBP CREB binding protein
CD38 cyclic ADP-ribose hydrolase
CNS central nervous system
CREB cAMP response element-binding protein
DLK dual leucine zipper-bearing kinase
ΔΨm mitochondrial membrane potential
DRP dynamin-like protein
ERK extracellular signal-regulated kinase
FDA United States Food and Drug Administration
FIS fission protein
GSK glycogen synthase kinase
JNK c-Jun N-terminal kinase
MAPK mitogen-activated protein kinase
Mcl myeloid leukemia cell differentiation protein
MEK MAPK kinase
MEKK MAPK kinase kinase
Mfn mitofusin
MKK4/7 dual specificity MAPK kinases 4 and 7
MKP MAPK phosphatase
MMP matrix metalloproteinase
mPT mitochondrial permeability transition
mtDAMP mitochondria-derived damage-associated molecular pattern
mTOR mechanistic (previously mammalian) target of rapamycin
mTORC mTOR complex
NEMO nuclear inhibitor of NF-κB kinase-γ
NF-κB nuclear factor-κB
NOS nitric oxide synthase
Nrf2 nuclear factor erythroid 2-related factor 2
OPA optic atrophy protein
OMA mitochondrial metalloendopeptidase
PAR poly(ADP-ribose) (PAR) polymerase
PARP poly(ADP-ribose) polymerase
PGC-1α peroxisome proliferator–activated receptor γ coactivator-1α
PI3K phosphatidylinositol-3 kinase
PINK PTEN-induced putative kinase
PTEN phosphatase and tensin homologue deleted on chromosome 10
PTP permeability transition pore
PUMA p53 upregulated modulator of apoptosis
Raf rapidly accelerated fibrosarcoma protein
RNS reactive nitrogen species
ROS reactive oxygen species
SAB mitochondrial SH3-domain binding protein 5
SIRT sirtuin; mono-ADP-ribosyltransferase
Smac second mitochondria-derived activator of caspase
TIM translocase of the inner membrane
TOM translocase of the outer membrane
VDAC voltage-dependent anion channel