Figure 1.
Decrease in transplanted cells occurs within 2 d post-TP, after which time there is no further decrease in cell number; 2 × 106 GFP-luc SCs were transplanted into the injured spinal cord 7 d postinjury. Transplanted cell survival was assessed in live rats by in vivo bioluminescent imaging (A). The amount of light produced by luciferase activity was quantified daily in the IVIS following D-luciferin administration for up to 7 d (days 1–3, n = 8–9; days 4–7, n = 3–5). Following tissue collection, the number of surviving GFP+ transplanted cells was quantified at 3 d (n = 3) or 7 d (n = 4) post-TP in the fixed, sectioned spinal cords by stereology (B). Mean ± SEM; *p = 0.004. Figure Contributions: Veena Kandaswamy and Kerri Scorpio performed the experiment. Caitlin Hill analyzed the data.