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. 2020 Apr 23;21(8):2983. doi: 10.3390/ijms21082983

Figure 4.

Figure 4

CA-IX inhibition allows the increased expression of apoptotic protein p53 in MDA-MB-231 and A549 cells. MDA-MB-231 (A,B) and A549 (C,D) were treated SLC-0111 and AA-06-05 [100–200 µM] for 1 h. The treatments were performed under experimental condition of medium with 1% FBS. Signals were evaluated through western blot and β-actin was used to normalize loading. For each experimental condition, Arbitrary Densitometry Units (A.D.U.) ± SD were reported as p53/β-actin vs basal control. (n = 3). * p < 0.05, ** p < 0.01 vs. untreated cells (Ctr).