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. 2020 Apr 23;21(8):2983. doi: 10.3390/ijms21082983

Figure 6.

Figure 6

CA-IX inhibition reduces the migration ability of MDA-MB-231 and A549 cells. In suspension tumor cells were treated with a sub-toxic dose [50 µM] of SLC-0111 and AA-06-05, for 30min. To assess the migration ability of MDA-MB-231(A,B) and A549 (C,D), the Boyden Chamber assay was performed with cells suspended in basal condition of medium with 0.1% FBS, and toward two serum gradients: 1% FBS (A,C) and 5% FBS (B,D) added in the lower compartments. Data were reported as counted cells for each well (n = 3). * p < 0.05 and ** p < 0.01 vs. untreated cells (Ctr).