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Functional roles of lncRNA in tumor metabolism. LncRNAs regulate target gene-mediated glucose metabolism (A) and mitochondrial function (B) in cancer. The role of lncRNA-mediated liver kinase B1 (LKB1)/AMP-activated protein kinase (AMPK) pathways (C), hypoxia-inducible factor 1α (HIF1α) (D), and p53 (E) in tumor cells was shown.
