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. 2020 Apr 23;21(8):2993. doi: 10.3390/ijms21082993

Figure 5.

Figure 5

Effects of vascularized tissues on the growth and morphology of U87 MCTS. Confocal images of MCTSs without (A) and with (B) vascularized tissues. The scale bar represents 200 μm or (B (ⅰ,ⅱ)) 100 μm. (C) Area, (D) height, (E) aspect ratio and (F) volume of tumours were measured for MCTSs with/without vascularized tissues. Data were obtained using 4–6 MCTSs in two tissues for each sample. Student’s t-test; ** p < 0.01, *** p < 0.001; “NS” denotes “not significant”. (G) mRNA Expressions of N-cadherin and vimentin. All experiments were performed in triplicate. Student’s t-test; * p < 0.05, ** p < 0.01, *** p < 0.001.