Table 2.
Up-regulated genes in DFCM groups as compared to KM1 group (control).
| Functions | Gene | DFCM-KM1 | DFCM-KM2 | DFCM-FM |
|---|---|---|---|---|
| Extracellular Matrix (ECM) Structural Constituents | COL1A2 | 8.08 ± 4.84 | 6.35 ± 1.13 | 3.77 ± 8.17 |
| COL5A2 | 5.05 ± 3.01 | 3.10 ± 1.02 | 2.26 ± 4.82 | |
| COL3A1 | 5.72 ± 4.16 | 4.37 ± 3.09 | 3.43 ± 8.00 | |
| COL1A1 | 3.50 ± 12.86 | 3.83 ± 2.26 | 11.55 ± 4.82 | |
| COL5A1 | 4.60 ± 9.44 | 4.85 ± 2.34 | 4.05± 7.67 | |
| COL5A3 | 5.96 ± 13.83 | 10.09 ± 11.92 | 4.13 ± 3.76 | |
| COL4A1 | 4.79 ± 4.57 | 2.84 ± 0.23 | 9.6 ± 15.30 | |
| Extracellular Matrix (ECM) Remodelling Enzymes | CTSV | 6.33 ± 2.66 | 2.72 ± 0.94 | 12.32 ± 10.53 |
| MMP9 | 4.89 ± 3.05 | 2.59 ± 2.01 | 8.62 ± 3.64 | |
| F13A1 | 2.33 ± 5.30 | 6.16 ± 2.56 | 7.31 ± 4.94 | |
| PLAT | 1.71 ± 3.20 | 2.57 ± 1.81 | 1.01 ± 6.04 | |
| MMP7 | 9.76 ± 8.12 | 4.56 ± 2.81 | 1.67 ± 2.36 | |
| SERPINE1 | 4.24 ± 1.70 | 1.86 ± 0.59 | 2.26 ± 6.34 | |
| PLAU | 4.24 ± 0.85 | 2.06 ± 0.99 | 4.49 ±2.66 | |
| TIMP1 | 3.59 ± 1.85 | 1.84 ± 1.15 | 1.70 ± 0.98 | |
| Growth Factors | FGF7 | 3.19 ± 0.83 | 7.32 ± 8.93 | 5.15 ± 9.10 |
| CSF3 | 0.18 ± 2.25 | 4.10 ± 0.26 | 2.08 ± 4.71 | |
| TNF | 9.52 ± 17.77 | 7.36 ± 4.63 | 1.08 ± 1.52 | |
| CSF2 | 7.37 ± 8.66 | 3.79 ± 1.10 | 12.03 ± 3.42 | |
| Inflammatory Cytokines & Chemokines | IL1B | 1.71 ± 2.48 | 6.49 ± 5.86 | 5.38 ± 4.40 |
| CCL7 | 0.54 ± 0.76 | 7.32 ± 10.69 | 5.15 ± 3.42 | |
| Cell Adhesion Molecules | ITGB5 | 5.25 ± 4.94 | 4.35 ± 4.37 | 4.29 ± 4.45 |
| WNT signalling | WNT5A | 1.13 ± 3.89 | 2.47 ± 0.89 | 0.85 ± 6.65 |