Table 2.
Cox univariate and multivariate regression analysis of pathological stage, TNM prognostic factors and DDX3X expression for overall survival in 500 renal cell carcinoma patients.
| Univariate | Multivariate | ||||
|---|---|---|---|---|---|
| Variable | Comparison | HR (95% CI) | p value | HR (95% CI) | p value |
| Gender | M:F | 0.951 (0.694–1.303) | 0.752 | 0.889 (0.564–1.4) | 0.612 |
| Stage | 3–4:1–2 | 4.287 (3.089–5.949) | <0.001 | 3.574 (1.672–7.639) | 0.001 |
| T | T3-4:T1-2 | 2.992 (2.136–4.191) | <0.001 | 0.701 (0.334–1.47) | 0.347 |
| N | N1:N0 | 2.794 (1.486–5.255) | 0.001 | 1.236 (0.638–2.392) | 0.53 |
| M | M1:M0 | 4.544 (3.303–6.251) | <0.001 | 2.263 (1.38–3.711) | 0.01 |
| DDX3X | High:Low | 0.589 (0.42–0.826) | 0.002 | 0.583 (0.359–0.946) | 0.029 |
Note: Cox proportional hazards regression was used to test the independent prognostic contribution of DDX3X after accounting for other potentially important covariates. Abbreviation: F: female; M: male; HR: hazard ratio; CI: confidence interval.