Table 2.
Multivariable Cox proportional hazards model for comorbidities and survival analysis.
| Variable | Alcoholic Cirrhosis | Non-Alcoholic Cirrhosis | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted Hazard Ratio | a Adjusted Hazard Ratio | Unadjusted Hazard Ratio | a Adjusted Hazard Ratio | |||||||||
| Risk Ratio | 95% CI | p-Value | Risk Ratio | 95% CI | p-Value | Risk Ratio | 95% CI | p-Value | Risk Ratio | 95% CI | p-Value | |
| Sex | ||||||||||||
| Male | 0.703 | 0.371–1.335 | 0.282 | 0.777 | 0.399–1.512 | 0.458 | 1.114 | 1.008–1.232 | 0.034 | 1.241 | 1.119-1.376 | <0.001 |
| Female (reference) | ||||||||||||
| Age (years) | ||||||||||||
| 40–49 (reference) | ||||||||||||
| 50–59 | 1.255 | 0.877–1.795 | 0.214 | 1.335 | 0.923–1.930 | 0.124 | 1.070 | 0.883–1.297 | 0.489 | 1.114 | 0.918–1.351 | 0.275 |
| 60–69 | 0.793 | 0.465–1.353 | 0.395 | 0.848 | 0.489–1.472 | 0.559 | 1.258 | 1.041–1.521 | 0.017 | 1.344 | 1.105–1.635 | 0.003 |
| >69 | 2.541 | 1.540–4.193 | <0.001 | 2.004 | 1.115–3.603 | 0.020 | 2.487 | 2.104–2.939 | <0.001 | 2.675 | 2.229–3.212 | <0.001 |
| Comorbidity | ||||||||||||
| Coronary heart disease | 1.098 | 0.700–1.723 | 0.685 | 1.170 | 0.703-1.948 | 0.546 | 1.129 | 1.014-1.257 | 0.027 | 0.886 | 0.785-1.000 | 0.050 |
| Cerebrovascular disease | ||||||||||||
| Hemorrhage | 1.799 | 0.883–3.666 | 0.106 | 1.578 | 0.732–3.400 | 0.244 | 1.356 | 1.077–1.706 | 0.01 | 1.377 | 1.090–1.738 | 0.007 |
| Ischemia | 1.279 | 0.692–2.361 | 0.432 | 0.879 | 0.439–1.758 | 0.715 | 1.221 | 1.071–1.393 | 0.003 | 0.950 | 0.827–1.092 | 0.470 |
| Hypertension | 0.845 | 0.614–1.162 | 0.300 | 0.684 | 0.471–0.994 | 0.046 | 1.059 | 0.960–1.167 | 0.253 | 0.783 | 0.698–0.878 | <0.001 |
| Heart failure | 1.393 | 0.754–2.571 | 0.290 | 0.981 | 0.477–2.016 | 0.958 | 1.510 | 1.328–1.715 | <0.001 | 1.136 | 0.987–1.308 | 0.076 |
| Diabetes mellitus | 0.958 | 0.683–1.343 | 0.802 | 1.056 | 0.732–1.524 | 0.771 | 1.047 | 0.949–1.156 | 0.360 | 1.090 | 0.981–1.212 | 0.110 |
| Chronic kidney disease | 2.137 | 1.488–3.070 | <0.001 | 2.276 | 1.520–3.409 | <0.001 | 1.881 | 1.698–2.084 | <0.001 | 1.751 | 1.571–1.951 | <0.001 |
| Hyperlipidemia | 0.452 | 0.293–0.699 | <0.001 | 0.447 | 0.282–0.708 | <0.001 | 0.574 | 0.505–0.653 | <0.001 | 0.571 | 0.499–0.652 | <0.001 |
| Chronic obstructive pulmonary disease | 1.227 | 0.800-1.883 | 0.348 | 1.240 | 0.789-1.951 | 0.351 | 1.346 | 1.205-1.502 | <0.001 | 0.994 | 0.883-1.119 | 0.920 |
a Adjustments were made for sex, age, residence, income, coronary artery disease, cerebrovascular disease, hypertension, heart failure, diabetes mellitus, chronic kidney disease, hyperlipidemia, and chronic obstructive pulmonary disease.