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. 2020 Apr 19;21(8):2856. doi: 10.3390/ijms21082856
AB antibody
Akt protein kinase B
AML acute myeloid leukemia
APC antigen presenting cell
AUC area under curve
β2m beta-2 microglobulin
B-ALL B cell acute lymphoblastic leukemia
BCMA B cell maturation antigen
BCR B cell receptor
BTK Bruton’s tyrosine kinase
CAIX carbonic anhydrase IX
CAR chimeric antigen receptor
CD cluster of differentiation
CDK4/6 cyclin dependent kinase 4 and 6
CLL chronic lymphocytic leukemia
CR complete remission
CRC colorectal cancer
CRS cytokine release syndrome
CT computed tomography
CTLA-4 cytotoxic T-lymphocyte protein 4
CTx chemotherapy
DLBCL diffuse large B cell lymphoma
DLT dose limiting toxicity
dMMR mismatch repair deficiency
EGFR epidermal growth factor receptor
EGFRvIII epidermal growth factor receptor variant III
ERK extracellular signal-regulated kinase
FDA Food and Drug Administration
GD2 disialoganglioside
GVHD graft-versus-host disease
GSK-3 serine/threonine kinase glycogen synthase kinase 3
HCC hepatocellular carcinoma
HER2 human epidermal growth factor receptor 2
HL Hodgkin’s lymphoma
HLA human leukocyte antigen
HNSCC head and neck squamous cell carcinoma
HR hazard ratio
ICI immune-checkpoint inhibitors
IHC immunohistochemistry
IL interleukin
IFNγ interferon-gamma
IRAE immune-related adverse events
ITK interleukin-2 inducible T cell kinase
ITIM immunoreceptor tyrosine-based inhibitory motif
ITSM immunoreceptor tyrosine-based switch motif
JAK Janus kinase
LAG-3 lymphocyte-activation gene 3
LAT linker for activation of T cells
Lck lymphocyte-specific protein tyrosine kinase
LOH loss of heterozygosity
LOHHLA Loss of Heterozygosity in Human Leukocyte Antigen
MAPK mitogen-activated protein kinase
MCL mantle cell lymphoma
MHC major histocompatibility complex
MRT magnetic resonance tomography
MSI-H microsatellite instability
mTOR mechanistic target of rapamycin
MUC1 mucin 1
NFAT nuclear factor of activated T cells
NK cell natural killer cell
NKT cell natural killer T cell
NFKB nuclear factor kappa-light-chain-enhancer of activated B cells
NHL non-Hodgkin lymphoma
NR2F6 nuclear receptor subfamily 2 group F member 6
NSCLC non-small cell lung cancer
OS overall survival
ORR overall response rate
PD-1 programmed cell death protein 1
PD-L1 programmed cell death-ligand 1
PET positron emission tomography
PFS progression-free survival
PI3K phosphatidylinositol 3-kinase
PKC protein kinase C
PLCg phospholipase C gamma 1
PMBCL primary mediastinal B cell lymphoma
PR partial remission
RCC renal cell carcinoma
RGMb repulsive guidance molecule B
SBRT stereotactic body radiotherapy
scFV single-chain variable fragment
SCNA somatic copy number alterations
SHP small heterodimer partner
shRNA small hairpin RNA
SPECT single photon emission computed tomography
SUV standardized uptake value
TAP transporter associated with antigen processing
tbx21 T-box transcription factor 21
TCGA The Cancer Genome Atlas
TCR T cell receptor
TFH T follicular helper cell
TFR T follicular regulatory cell
TH2 T helper 2 cell
TILs tumor infiltrating lymphocytes
TIM-3 T cell membrane protein 3
TKI tyrosine kinase inhibitor
TMB tumor mutational burden
TNBC triple negative breast cancer
TNFα tumor necrosis factor alpha
TOX thymocyte selection-associated high mobility group box protein TOX
TPS tumor proportion score
Treg regulatory T cell
Tx therapy
VEGF vascular endothelial growth factor
VEGFR vascular endothelial growth factor receptor
ZAP70 zeta chain-associated protein kinase 70