Figure 7.

Flowchart of the study. The experiment was started with 8-week-old non-diabetic db+ and diabetic db/db mice. Diabetic mice were randomly assigned for treatment with a vehicle, empagliflozin, linagliptin, or combination of empagliflozin and linagliptin. The total duration of the experiment was 8 weeks. Procedures 1 and 2 included body weight measurement, body composition assessment, blood plasma and urine sampling. EMPA, empagliflozin-treated db/db mice; LINA, linagliptin-treated db/db mice; EMPA + LINA, empagliflozin–linagliptin-treated db/db mice.