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. 2020 Apr 20;21(8):2864. doi: 10.3390/ijms21082864

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Malformation of zebrafish embryos exposed to LAS and SAS. (A) The SAS/LAS-treated embryos (0, 0.1, 1, 10 μg/mL) revealed different malformed phenotypes at 96 hpf. J, jaw malformation; PE, pericardial edema; OY, opaque yolk; AC, axial curvature; Y, yolk sac edema; E, eye malformation. (B) Quantification of the survival rate and specific malformation rate, including notochord malformation, yolk edema, axis malformation, and heart malformation. The total malformation indicates the sum of the specific malformation rate. The values are presented as the mean ± SEM.