4EBP1	eIF4E -binding protein 1
AML	acute myeloid leukemia
AMPK	AMP-activated protein kinase
APL	acute promyelocytic leukemia
BAD	BCL2 associated agonist of cell death
BCL2	B-cell lymphoma-2
CR	complete remission
CRi	complete remission with incomplete recovery
CREB	cAMP response element-binding protein
DFS	disease free survival
eIF4E	eukaryotic initiation factor-4E
ERK	extracellular signal-regulated kinase
FKBP38	FK506-binding protein 38
FLT3	fms like tyrosine kinase 3
GAB2	GRB2 associated binding protein
GAP	GTPase-activating protein
GLUT1	glucose transporter 1
GPCR	G-protein-coupled receptor
GRB2	growth factor receptor-bound protein 2
GSK3	glycogen synthase kinase 3
HSC	hematopoietic stem cell
HSPC	hematopoietic stem/progenitor cell
IGF	insulin growth factor
IRS	insulin receptor substrates
IDH	isocitrate dehydrogenase
ITD	internal tandem duplication
LSC	leukemic stem cell
MEK	MAPK ERK kinase
mLST	mammalian lethal with SEC13 protein
mSIN1	mammalian stress-activated protein kinase-interacting protein 1
mTOR	mammalian target of rapamycin
mTORC1	mTOR complex 1
mTORC2	mTOR complex 2
NPM1	nucleophosmin 1
OS	overall survival
PDK1	phosphoinositide-dependent kinase-1
PFK2	phosphofructokinase-2
PH	pleckstrin-homology
PI3K	phosphoinositide 3-kinase
PIKK	PI3K-related kinase
PIP2	phosphatidylinositol 4,5-bisphosphate
PIP3	phosphatidylinositol 3,4,5- trisphosphates
PKC	protein kinase C
PMA	Phorbol 12-myristate 13-acetate
PR	partial remission
Pras40	proline-rich Akt substrate of 40 kDa
PTEN	protein deleted on chromosome 10
RSK	Ribosomal S6 kinase
RHEB	Ras homologue enriched in brain (RHEB)
RTK	receptor tyrosine kinase
S6K	S6 kinase
SH2	Src Homology 2
SHIP1	SH2 domain-containing inositol 5-phosphatases 1
SHIP2	SH2 domain-containing inositol 5-phosphatases 2
SREBF1	sterol regulatory element-binding transcription factor 1
TCA	tricarboxylic acid
TKD	tyrosine kinase domain
TSC	tuberous sclerosis complex