Table 1.
miRNAs and their target genes in lung development and diseases, as shown in cited articles.
| miRNA | Molecular Target(s) |
|---|---|
| Lung Development | |
| miR-326 | Smo and Gli2 |
| miR-142-3p | Apc |
| miR-449a | MYCN |
| miR-421 | Fgf10 |
| miR-302/367 | Cdkn1a, RbI2, Tiam1, and Lis1 |
| Lung Diseases | |
| COPD | |
| miR-145-5p | KLF5 |
| miR-149-3p | TLR-4 |
| miR-218 | TNFR1 |
| miR-3202 | FAIM2 |
| miR-223 | HDAC2 |
| miR-181c | CCN1 |
| miR-195 | PHLPP2 |
| miR-664a-3p | FHL1 |
| Asthma | |
| miR-744 | TGFB1 |
| miR-943-3p | SFRP4 |
| miR-30a | ATG5 |
| Pulmonary Fibrosis | |
| miR-18a-5p | TGFBR2 |
| miR-153 | TGFBR2 |
| miR-1343 | TGFBR1 and TGFBR2 |
| miR-9-5p | TGFBR2 and NOX4 |
| miR-101 | TGFBR1, FZD4, and FZD6 |
| miR-486-5p | SMAD2 |
| miR-323a-3p | SMAD2 and TGFA |
| miR-489 | Smad3 |
| miR-133a | TGFBR1, CTGF, and Col1a1 |
| miR-542-5p | Itga6 |
| miR-29a | LOXL2 and SERPINH1 |
| miR-708-3p | ADAM17 |
| miR-338-5p | LPA1 |
| PAH | |
| miR-205-5p | MICAL2 |
| miR-455-3p-1 | FGF7 |
| miR-181a/b-5p | endocan |
| miR-27a | Smad5 |
| miR-30a-5p | YKL-40 |